IntroductionAngiotensin-converting enzyme 2 (ACE2) played an important role in the renin-angiotensin-aldosterone system (RAAS) and it was proved to be renoprotective in renal disease.Urinary angiotensin-converting enzyme 2 (uACE2) has been shown to reflect renal injury in human and experimental studies, but its role in feline kidney disease remains
Introduction Hypertensive disorder of pregnancy is the second commonest causes of bearing cover maternal death globally.Different public health studies were conducted on hypertensive disorder of pregnancy which presented inconsistent result.Therefore, this systematic review and meta-analysis was commenced to summarize the findings conducted in seve
Abstract Overfeeding triggers homeostatic compensatory mechanisms that counteract weight gain.Here, we show that both lean and diet-induced obese (DIO) male mice exhibit a potent and prolonged inhibition of voluntary food intake following overfeeding-induced weight gain.We reveal that FGF21 is dispensable for this defense against weight gain.Target
Abstract Background Transcriptional control of gene expression is a widely utilized regulatory mechanism in synthetic biology, biotechnology and recombinant protein production.It is achieved by utilization of naturally occurring promoters responding to nutrients or chemicals.Despite their regulatory properties, these promoters often possess feature
The article analyzes the role of presuppositions, which are widely used in the Spanish political and journalistic discourse as a means of manipulating language, and are focused Highlighters on strengthening the management capacity of language to provide a hidden impact on recipients.Presuppositions implicitly convey information; they are convenient